Noteworthy collections at the museum include Roanoke Dolls, Camp Opelika items (a WW II POW camp), and area business history. Early sound recording technology items, agricultural implements, fire fighting tools, household and mercantile artifacts on exhibit all give visitors a look at the vast technological changes which have taken place during the last century. In addition, the museum has a wonderful musical instrument collection which includes a restored 1899 pump organ.

Special temporary exhibits from both the museum’s permanent collection and traveling exhibits are scheduled periodically and cover a wide range of subjects. Previous special exhibits have included a traveling exhibition from the Smithsonian, a quilt exhibit, an embroiderer’s exhibit, pine needle baskets, depression era Alabama photographs, hat exhibit, toys, dolls and game exhibit and more.